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Keeping cows on feed and in production

Why immune modulation matters in the transition period and after mastitis

Milk production doesn’t drop because only one thing goes wrong. It drops when cows don’t recover fast enough after predictable stress moments. Calving, early lactation, vaccination pressure, or an inflammatory event like clinical mastitis (Ingvartsen & Moyes, 2013). What you often see first is a change in behavior: cows go off feed, rumination falls, their temperature becomes unstable and performance follows. 

For years, most on-farm “quick fixes” have focused on suppressing visible signs. Especially with fever and discomfort. But making a good recovery is more than symptom control. Inflammation is not just a problem to shut down; it is also part of the biology of recovery: with tissue repair, immune cell recruitment, getting cows back to normal function). 

Rumination is essential for fresh and sick dairy cows because it supports rumen stability, feed intake, and overall recovery. Around calving and during illness, rumination often drops, increasing the risk of metabolic and health disorders. For dairy farmers, rumination is a powerful early indicator of problems and directly linked to milk production, fertility, and profitability. A fast recovery of rumination means the cow is back to normal intake and rumen function, reducing the risk of further complications. The quicker rumination returns, the faster the cow can perform, stay healthy, and deliver optimal results. 

From “symptom suppression” to “supporting recovery” 

That’s where immune modulation comes in. Immune modulation means adjusting an animal’s immune system so it works properly. It can either boost the immune response when it’s too weak or calm it down when it’s too strong. 
The goal is to keep the immune system balanced and effective. This helps animals stay healthier and fight disease better. 

The improved AHV Aspi Tablet is built on the same core principles, now supported by stronger scientific substantiation around immune modulation: supporting a balanced inflammatory response while maintaining the cow’s natural recovery processes.  

What the improved Aspi Tablet is designed to do  

The improved Aspi Tablet is positioned for proactive use during high-risk periods such as calving and early lactation, you can also use it in reactive situations where cows need help getting back to normal after an inflammatory challenge.  

The product allows for easy integration into routine management because it is a complementary feed solution, designed to fit feed regulatory frameworks, without milk or meat withdrawal constraints.  

What field trials show (Aspi vs NSAID example) 

In an on-farm comparison (40 cows in AHV group, 40 cows in NSAID group), cows flagged with clinical mastitis showed clear differences in recovery dynamics: 

Rumination returned faster in cows receiving Aspi 
*returning closer to normal between roughly 48 hours 
*compared to 120 hours—and this between-treatment difference is reported as statistically significant in the trial (p = 0.031).  

  • Repeats (temperature spikes/flags) within the first 20 days were lower in the Aspi group, with the material reporting a statistically significant difference (p = 0.001).  
  • The same trial notes that cows treated with Aspi showed patterns consistent with more stable recovery (rumination and temperature stability) versus a “fast drop then rebound” pattern described for Ketoprofen. 

In short: AHV Aspi is not “a stronger fever reducer”, you create a more stable recovery. Getting cows back to feed intake and normal behavior faster, and reducing the risk of repeated setbacks.  

Why that matters economically (even when milk price is under pressure) 

When cows recover faster: 

  • They spend fewer days with suppressed intake; 
  • They stabilize milk production earlier; 
  • They’re less likely to need repeat interventions. 

The results explicitly connect immune modulation to outcomes like earlier restoration of rumination and more stable normalization of body temperature, showing recovery support “beyond symptoms.”  

If your goal is “keep cows on feed and back in performance as fast as possible,” the practical things to watch are the ones you already track: rumination, temperature stability, activity and whether cows get flagged again. 

Sources

Beauchemin, K. A. (2018). Invited review: Current perspectives on eating and rumination activity in dairy cows. Journal of Dairy Science, 101(6), 4762–4784.
Soriani, N., Trevisi, E., & Calamari, L. (2012). Relationships between rumination time, metabolic conditions, and health status in dairy cows during the transition period. Journal of Animal Science, 90(12), 4544–4554.
Schirmann, K., Chapinal, N., Weary, D. M., Heuwieser, W., & von Keyserlingk, M. A. G. (2016). Rumination and feeding behavior before and after calving in dairy cows. Journal of Dairy Science, 99(4), 2733–2744.
Stangaferro, M. L., Wijma, R., Caixeta, L. S., Al-Abri, M. A., & Giordano, J. O. (2016). Use of rumination and activity monitoring for the identification of dairy cows with health disorders. Journal of Dairy Science, 99(9), 7395–7410.

When to use Aspi?

  1. IMMEDIATELY AFTER CALVING

    Read more

  2. 7 DAYS AFTER CALVING

    Read more

  3. 4-8 WEEKS BEFORE DRY-OFF

    Read more

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