Biofilm formation
Bacteria form and maintain biofilm through the process of quorum sensing.
Biofilm eradication
AHV’s proprietary technology disrupts the quorum sensing process and eradicates biofilm structure.
Clearing
Without the “protection” of biofilm, pathogenic bacteria become susceptible to immune cells, removing the need for antibiotics.
Figure 1: Our Fundamental lab research, our basis for our product development
AHV LAB: BIOFILM ERADICATION STUDIES
Our team of microbiologists cultivate a wide range of bacterial biofilm in AHV’s BSL-2 laboratory. Via these bacterial biofilms, AHV is able to select the plant molecules that are able to avoid biofilm formation (MBIC) or to eradicate existing biofilms (MBEC).
This research led to innovative pending patented anti-biofilm compounds (QQ 1,2,3), or QSIs extracted from natural resources. With our wide range of innovations and solutions for animal health, AHV supports and empowers the farming community through new standards for animal health management and care.
In multiple independent studies, mature biofilms (figure 3X) were examined using two different dosages (figure 3: Control and high dosage) of the AHV QSI Technology active anti biofilm compounds (QQ-2).
Figure 2: Untreated bacterial biofilm (AHV International, 2021)
Figure 3: Biofilm eradication with AHV QSI Technology active compounds (AHV International, 2021)
Bacterial biofilm visualized from the top in a Nikon confocal laser scanning microscope. Green signals represent the living bacteria, red signals represent inactive bacteria. The top panel resembles the control with untreated biofilm. The bottom panel shows biofilm treated with active AHV QSI Technology compounds. The results of the core AHV QSI Technology were measured after one day (figure 3). A clear reduction / breakdown of the biofilm was already established because of a high amount of inactive bacteria and a few living bacteria.
Product strategy
Based on mode of action
Figure 4: AHV Product Strategy (AHV International, 2021)
